Qualification at a Glance
The Pearson Edexcel Level 3 Advanced GCE in Biology B consists of three externally examined papers and the Science Practical Endorsement. Students are expected to carry out the 16 core practical experiments identified in the content. All assessments are completed in May/June in a single year.
Paper 1: Advanced Biochemistry, Microbiology, and Genetics
- Assessment: 1 hour 45 minutes, 90 marks
- 30% of total qualification
Paper 2: Advanced Physiology, Evolution, and Ecology
- Assessment: 1 hour 45 minutes, 90 marks
- 30% of total qualification
Paper 3: General and Practical Principles in Biology
- Assessment: 2 hours 30 minutes, 120 marks
- 40% of total qualification
Science Practical Endorsement
- Internally assessed and externally monitored by Pearson
Detailed Content Overview
Topic 1: Biological Molecules
- Carbohydrates
- Lipids
- Proteins
- DNA and Protein Synthesis
- Enzymes
- Inorganic Ions
- Water
Topic 2: Cells, Viruses, and Reproduction of Living Things
- Eukaryotic and Prokaryotic Cell Structure and Function
- Viruses
- Eukaryotic Cell Cycle and Division
- Sexual Reproduction in Mammals
- Sexual Reproduction in Plants
Topic 3: Classification and Biodiversity
- Classification
- Natural Selection
- Biodiversity
Topic 4: Exchange and Transport
- Surface Area to Volume Ratio
- Cell Transport Mechanisms
- Gas Exchange
- Circulation
- Transport of Gases in the Blood
- Transfer of Materials between the Circulatory System and Cells
- Transport in Plants
Topic 5: Energy for Biological Processes
- Aerobic Respiration
- Glycolysis
- Link Reaction and Krebs Cycle
- Oxidative Phosphorylation
- Anaerobic Respiration
- Photosynthetic Pigments
- Photosynthesis
Topic 6: Microbiology and Pathogens
- Microbial Techniques
- Bacteria as Pathogens
- Action of Antibiotics
- Antibiotic Resistance
- Other Pathogenic Agents
- Problems of Controlling Endemic Diseases
- Response to Infection
Topic 7: Modern Genetics
- Using Gene Sequencing
- Factors Affecting Gene Expression
- Stem Cells
- Gene Technology
Topic 8: Origins of Genetic Variation
- Origins of Genetic Variation
- Transfer of Genetic Information
- Gene Pools
Topic 9: Control Systems
- Homeostasis
- Chemical Control in Mammals
- Chemical Control in Plants
- Structure and Function of the Mammalian Nervous System
- Nervous Transmission
- Effects of Drugs on the Nervous System
- Detection of Light by Mammals
- Control of Heart Rate in Mammals
- Osmoregulation and Temperature Regulation
Topic 10: Ecosystems
- The Nature of Ecosystems
- Energy Transfer Through Ecosystems
- Changes in Ecosystems
- Human Effects on Ecosystems
Practical Skills
Practical skills are central to any study of biology and are developed through 16 core practical activities:
- Investigate a factor affecting the initial rate of an enzyme-controlled reaction.
- Use a light microscope to observe and measure cells.
- Make a temporary squash preparation of a root tip to show stages of mitosis.
- Investigate the effect of sucrose concentrations on pollen tube growth.
- Investigate the effect of temperature on beetroot membrane permeability.
- Determine the water potential of plant cells.
- Dissect an insect to show the structure of the gas exchange system.
- Investigate factors affecting water uptake by plant shoots using a potometer.
- Investigate factors affecting the rate of aerobic or anaerobic respiration using a respirometer.
- Investigate the effects of different wavelengths of light on the rate of photosynthesis.
- Investigate the presence of different chloroplast pigments using chromatography.
- Investigate the rate of growth of bacteria in liquid culture.
- Isolate individual species from a mixed culture of bacteria using streak plating.
- Investigate the effect of gibberellin on the production of amylase in germinating cereals.
- Investigate the effect of different sampling methods on estimates of the size of a population.
- Investigate the effect of one abiotic factor on the distribution or morphology of one species.
Science Practical Endorsement
The Science Practical Endorsement assesses practical skills in the lab. It is a compulsory requirement, reported separately on the student’s certificate. Teachers assess students against Common Practical Assessment Criteria (CPAC).
Criteria include:
- Follows written procedures
- Applies investigative approaches and methods when using instruments and equipment
- Safely uses a range of practical equipment and materials
- Makes and records observations
- Researches, references, and reports
Assessment Objectives and Weightings
- AO1: Demonstrate knowledge and understanding of scientific ideas, processes, techniques, and procedures - 31-33%
- AO2: Apply knowledge and understanding in various contexts - 41-43%
- AO3: Analyse, interpret, and evaluate scientific information, ideas, and evidence - 25-27%
Access Arrangements and Reasonable Adjustments
Pearson provides various access arrangements and reasonable adjustments to ensure fair access for all students, compliant with the Equality Act 2010.